SASP Atlas
SASP Atlas
Unbiased mass spectrometry analysis of the senescence-associated secretory phenotype (SASP) of cultured primary human cells. For each experiment below, the SASP was determined by comparing the secretomes of senescent cells to mock- or vehicle-treated quiescent control cells. Each spreadsheet contains a list of proteins identified in the secretome, fold changes, p-values, q-values, peptide sequences, and other relevant annotations.
The soluble protein SASP of primary human fibroblasts (IMR90) 10 days post-irradiation.
The soluble protein SASP of primary human fibroblasts (HCA2) 9 days after treatment with the protease inhibitor Atazanivir.
The soluble protein SASP of primary human fibroblasts (HCA2) 14 days after treatment with the protease inhibitor Atazanivir.
The soluble protein SASP of primary human fibroblasts (IMR90) 4 days after induction of RAS overexpression.
The soluble protein SASP of primary human fibroblasts (IMR90) 7 days after induction of RAS overexpression.
The soluble protein SASP of primary human renal epithelial cells 10 days post-irradiation.
The exosome SASP of primary human fibroblasts (IMR90) 10 days post-irradiation.
The exosome SASP of primary human fibroblasts (IMR90) 7 days after RAS induction.